Transatlantic Networks of Excellence and Funded Networks

Transatlantic Networks of Excellence Program

The Leducq Foundation Transatlantic Networks of Excellence Program provides $7,000,000 over five years to teams of researchers working collaboratively in the areas of cardiovascular and neurovascular disease.
Details about the program are available in the Program Description.  As of 2020, the foundation has supported 66 networks, representing more than 400 investigators at 130 institutions in 21 countries.

Funded Networks of 2020

B cells in Cardiovascular Disease

  • European Coordinator: Christoph BINDER, Medical University of Vienna (Austria)
  • North American Coordinator: Filip SWIRSKI, Massachusetts General Hospital (USA)

Cytoskeletal regulation of cardiomyocyte homeostasis in health and disease

  • European Coordinator: Lucie CARRIER, University Medical Center Hamburg (Germany)
  • North American Coordinator: Benjamin PROSSER, Perelman School of Medicine, University of Pennsylvania (USA)

The Inflammatory-Fibrosis Axis in Ischemic Heart Failure: translating mechanisms into new diagnostics and therapeutics

  • European Coordinator: Florian LEUSCHNER, Heidelberg University Hospital (Germany)
  • North American Coordinator: Robert GROPLER, Washington University School of Medicine (USA)

Editing the Failing Heart

  • European Coordinator: Wolfram ZIMMERMANN, University Medical Center Göttingen (Germany)
  • North American Coordinator: Elizabeth MCNALLY, Northwestern University (USA)

Funded Networks of 2019

Cellular and systemic cholesterol transport in physiology and disease

  • European Coordinator: Elina IKONEN, University of Helsinki (Finland)
  • North American Coordinator: Peter TONTONOZ, University of California, Los Angeles (USA)

Fighting against sinus node dysfunction and associated arrhythmias

  • European Coordinator: Matteo MANGONI, CNRS, Montpellier (France)
  • North American Coordinator: Peter MOHLER, The Ohio State University, Columbus (USA)

Targeted Approaches for Prevention and Treatment of Anthracycline-Induced Cardiotoxicity

  • European Coordinator: Emilio HIRSCH, Università degli Studi di Torino (Italy)
  • North American Coordinator: Hossein ARDEHALI, Northwestern University, Chicago (USA)

Stroke-IMPaCT (Stroke – Immune Mediated Pathways and Cognitive Trajectories)

  • European Coordinator: Stuart ALLAN, University of Manchester (UK)
  • North American Coordinator: Marion BUCKWALTER, Stanford University (USA)

Funded Networks of 2018

Towards Precision Medicine with Human iPSCs for Cardiac Channelopathies

  • European Coordinator: Peter SCHWARTZ, University of Pavia (Italy)
  • North American Coordinator: Joseph WU, Stanford University School of Medicine, California (USA)

Clonal hematopoiesis and atherosclerosis

  • European Coordinator: Andrés HIDALGO, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid (Spain)
  • North American Coordinator: Alan TALL, Columbia University Medical Center, New York (USA)

Transcription factor Klf2 and cardiovascular disease

  • European Coordinator: Ralf ADAMS, Max Plank Institute for Molecular Biomedicine, Münster (Germany)
  • North American Coordinator: Martin SCHWARTZ, Yale University, New Haven (USA)

Defining the Roles of Smooth Muscle Cells and Other Extracellular Matrix Producing Cells in Late Stage Atherosclerotic Plaque Pathogenesis

  • European Coordinator: Gerard PASTERKAMP, University Medical Center, Utrecht (Netherlands)
  • North American Coordinator: Gary OWENS, University of Virginia, Charlottesville (USA)

Cure PhosphoLambaN induced Cardiomyopathy (Cure-PLaN)

  • European Coordinator: Pieter DOEVENDANS, Netherlands Heart Institute, Utrecht (Netherlands)
  • North American Coordinator: Evangelina KRANIAS, University of Cincinnati College of Medicine, Ohio (USA)

Funded Networks of 2017

The Transatlantic Networks of Excellence Program grant recipients of 2017 are listed below by project title and principal coordinators. For information about each network, please click on the project title.

Gut Microbiome as a Target for the Treatment of Cardiometabolic Diseases

  • European Coordinator: Fredrik BÄCKHED, University of Gothenburg, Gothenburg (Sweden)
  • North American Coordinator: Stanley HAZEN, Cleveland Clinic Foundation, Cleveland, OH (USA)

The sodium channel as a therapeutic target for prevention of lethal cardiac arrhythmias

  • European Coordinator: Connie R. BEZZINA, Academic Medical Center, University of Amsterdam, Amsterdam (Netherlands)
  • North American Coordinator: Mario DELMAR, New York University School of Medicine, New York, NY (USA)

ATTRACT: Arterial flow as attractor for endothelial cell migration

  • European Coordinator: Holger GERHARDT, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin (Germany)
  • North American Coordinator: Douglas MARCHUK, Duke University Medical Center, Durham, NC (USA)

Redox Regulation of Cardiomyocyte Renewal

  • European Coordinator: Miguel TORRES, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid (Spain)
  • North American Coordinator: Hesham A. SADEK, University of Texas Southwestern Medical Center, Dallas, TX (USA)

Potassium in Hypertension

  • European Coordinator: Olivier STAUB, University of Lausanne, Lausanne (Switzerland)
  • North American Coordinator: Paul WELLING, University of Maryland at Baltimore, Baltimore, MD (USA)