Research Highlights

Activation-repolarization mapping to guide VT-ablation without the need to induce the arrhythmia


Ruben Coronel

International Journal of Cardiology 2660. (13 June 2018): 1-2
Ventricular tachycardia and fibrillation are a major cause of sudden cardiac death, especially in the setting of chronic myocardial infarction (MI) [1]. These arrhythmias are mostly based on re-entry [1] and depend on the combination of a trigger (usually a critically timed premature activation) and an arrhythmogenic substrate. Surviving myocardial bundles that penetrate the scar tissue form the substrate and are the basis for a long activation delays across the myocardial scar. [2] The site(s) where the wavefronts exit from the scar can be targeted by ablation therapy.