Transatlantic Network on Hypertension – Renal Salt Handling in the Control of Blood Pressure

European Coordinator:
  • Bernard C. ROSSIER, University of Lausanne (Switzerland)
North American Coordinator:
  • Steven C. HEBERT († 15/04/2008)/Richard LIFTON, Yale University, New Haven (USA)
  • Gerardo GAMBA, National University, Mexico City (Mexico)
  • Xavier JEUNEMAITRE, Hôpital Européen Georges Pompidou INSERM U772/Collège de France, Paris (France)
  • Olivier STAUB, University of Lausanne (Switzerland)
  • Michel AZIZI, Université Paris-Descartes, Paris (France)
  • Michel BURNIER, University of Lausanne (Switzerland)
  • Cecilia CANESSA, Yale University, New Haven (USA)
  • Michael CAPLAN, Yale University, New Haven (USA)
  • Alain DOUCET, Institut des Cordeliers, Paris (France)
  • Jean-Daniel HORISBERGER (†1/04/2009), University of Lausanne (Switzerland)
  • Edith HUMMLER, University of Lausanne (Switzerland)
  • Frédéric JAISSER, Collège de France, Paris (France)
  • Laurent SCHILD, University of Lausanne (Switzerland)
  • Maria-Teresa TUSIE-LUNA, National University, Mexico City (Mexico)
  • Tong WANG, Yale University, New Haven (USA)

Over one billion people have hypertension—high blood pressure—and many suffer from its cardiovascular consequences: heart attack, stroke, and kidney failure. Although medication is available, therapy can be limited by unpleasant or dangerous side effects. One promising area of new development is based on the recognition that how the kidney handles salt could be critical in the onset and maintenance of hypertension. The members of this transatlantic network have all contributed significantly to our knowledge of how the complex metabolic pathways involving the excretion of sodium, potassium, calcium, and chloride are implicated in the control of blood pressure. Now together, with the help of a cadre of young researchers, they bring their collective expertise to expand our knowledge of the molecular and genetic basis of the disorder.