The autonomic nervous system (ANS) powerfully modulates cardiac physiology and plays a crucial role in pathophysiology. During the pathogenesis of heart disease, alterations in ANS leads to increased sympathetic and... read more →
The brain produces myriads of metabolic waste products that need to be removed through brain clearance for normal brain function. However, our knowledge on the drainage of these waste products... read more →
Our Network, the International Triglyceride Consortium (ITC), will examine mechanisms for plasma triglyceride (TG) metabolism and will create new drugs for lowering plasma TG levels and reducing the risk of... read more →
Advanced heart failure is common, deadly and warrants novel therapies. The only curative therapy is cardiac allotransplantation but it is limited due to the shortage of donor organs. Using genetically... read more →