Heart attacks and strokes are the most common consequences of atherosclerosis, a chronic inflammatory disease affecting arteries. Atherosclerosis develops when cholesterol accumulates as plaque in the vessel wall, where it ... read more →
Heart failure, the inability of the heart to pump enough blood through the body, is a consequence of a loss of heart muscle and/or a change in the properties of... read more →
Inflammation and fibrosis represent cardinal hallmarks of myocardial remodeling and heart failure progression. Despite a wealth of data documenting robust clinical associations, proof of concept causation, and putative disease mechanisms,... read more →
Genome editing has the capacity to transform treatment for genetic and non-genetic cardiovascular disorders. Genetic testing is now making it routine to decipher mutations responsible for heart failure, arrhythmias, and... read more →